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Logitech Signature M650

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Logitech Signature M650
Colour
Product typemouse
ConnectionBluetooth/radio
Multi-Device
Sensoroptical
Typenotebook
Sensor and control
Sensor resolution400 – 4000 DPI
Number of buttons4
Side buttons
Scroll wheels1
Inertial wheel
Additional features
quiet click
Connection and power supply
Power source1xAA
Battery life24 months
General
Suitable for left-handers
In boxUSB-A dongle
Size (LxWxH)107x62x38 mm
Weight101 g
Official Websitelogitech.com
Added to E-CatalogFebruary 2022
P/N
910-006253

910-006254

910-006255

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910-006275

910-006274

Ergonomic mouse designed for comfortable and performant work throughout the day. Logitech offers several models, and this particular version is designed for small and medium-sized hands, although there are also options for larger hands and for left-handers. The device has a symmetrical body shape with a soft zone for the thumb and rubber side pads to make it as comfortable to use as possible.

The main advantage lies in the several ways to connect to a computer or laptop: you can choose a Logi Bolt USB receiver or Bluetooth Low Energy technology. In any case, the mouse works without wires, and the range is up to 10 meters. At the same time, the Logitech Signature M650 is powered by an AA battery. One such battery is already included in the package, and it will last for approximately 2 years of battery life.

Also worth noting is the quiet operation thanks to Logitech's SilentTouch technology, which reduces the volume of clicks by 90%, customizable side buttons, sensor resolution up to 4000 DPI with an adjustment button on the bottom of the case, and a SmartWheel. With it, you can customize the scrolling as you need it, and automatically switch modes with one click.

E-Catalog UK editor, Mice
Mykola Boberskyi, edited 19.05.2026
The information in the model description is for reference purposes.
Always clarify the specifications and configuration of the product with the online store manager before purchasing.
Catalog Logitech 2026 - new arrivals, bestsellers, and the most relevant models Logitech.

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Model overview based on user reviews  
Logitech Signature M650 is a comfortable wireless office mouse with quiet clicks and a smooth scroll wheel. It offers Bluetooth and USB receiver connectivity, side buttons, and a shape suited to small and medium-sized hands. Users also praise its build quality and configurable smart buttons, but some report connection drops, left-click failures, and rubber surfaces becoming sticky over time. Customization is limited, and the scroll wheel lacks a dedicated free-scrolling switch.
Pros

Cons

A nice mouse, but only for one year.
15 December 2025 
I use it with a MacBook (without using a Bluetooth adapter), and occasionally (1-2 times a week) the connection disappears, the reset button doesn't help, so I have to remove the battery. After a year of use, issues with the left click started (it misses clicks). Over time, the rubber under the fingers wears out and becomes sticky, which is typical for other mice of this brand.
Convenient for me
Silent click
Inertia wheel
The keyboard skips clicks
Connection is lost
The rubber wears out and becomes sticky over time
Serge D.use Logitech Signature M650 more than year
The wireless mouse is very convenient to use
15 December 2024 
Before I was gifted this mouse, I only used wired ones. This mouse is very comfortable, especially the smart buttons that can be customized.
Durable and high-quality material, has fallen off the table multiple times, but still works, nothing has broken off. The design is pleasant to the touch. Smart buttons.
If you turn off Bluetooth, all smart button settings are lost, and you need to set them up again.
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